منابع مشابه
Satisfactory screening for cystic fibrosis with the BM meconium procedure.
The Boehringer Mannheim test (BM test) for cystic fibrosis has been applied to 15 734 neonates. A positive result occurred in 130, seven of whom were subsequently shown to have the disease. To our knowledge no cases have been missed. Tests have been performed centrally by experienced laboratory staff and the false-positive rate of 0.83% is considered acceptable. It is important to follow up wea...
متن کاملScreening for cystic fibrosis by examination of meconium.
Prosser, R., Owen, H., Bull, F., Parry, B., Smerkinich, J., Goodwin, H. A., and Dathan, J. (1974). Archives of Disease in Childhood, 49, 597. Screening for cystic fibrosis by examination ofmeconium. The value of detecting albumin in meconium as a screening procedure for cystic fibrosis (CF) has been assessed on 34,228 samples in South Wales and North Staffordshire over a 4-year period; simultan...
متن کاملScreening for cystic fibrosis in the newborn by meconium analysis.
During a 4-year routine screening programme for cystic fibrosis (CF) 15 464 specimens were examined for raised meconium albumin levels by a test strip method and by electroimmunoassay. The incidence of false-positive results was about 5 per 1000 specimens in either test. This could be reduced by 90% by determining the ratio of albumin : alpha-1-trypsin inhibitor (a ratio below 2.0 being conside...
متن کاملScreening for cystic fibrosis.
Neonatal screening for cystic fibrosis (CF) reduces short-term morbidity but its long term effects remain to be demonstrated. The best available method is the assay of immunoreactive trypsin in dried blood spots, and specificity can be improved by adding direct or indirect genetic analysis. Pregnancies known to be at risk of CF can also be screened by molecular methods, and affected pregnancies...
متن کاملScreening for cystic fibrosis.
Sir, In their Short Report on screening for cystic fibrosis, Vol. 47, pages 131-134, Drs. Cain, Deall, and Noble expressed the hope that their trial would stimulate other maternity units to carry out similar surveys so that the efficiency of the method could be more rapidly assessed. In 1969 we started developing an immunochemical method to analyse meconium for albumin, and since August 1971 we...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1978
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197804001-00362